Tadalafil (International)

Cialis is changing the way doctors and patients think about treating ED by offering two important benefits: a 36-hour window of opportunity for intimacy and the ability to take the tablet on an empty stomach or with a meal, without concern that high-fat food will reduce the absorption of the medicine. "What the marketplace tells us is that men and their partners are truly taking advantage of the benefits of Cialis," said Matt Beebe, U.S.

Cialis vs. Viagra side effects

Specifically, Cialis and Viagra may not be safe in some people with cardiovascular conditions since the medications affect circulation. Seek medical advice about using PDE5 inhibitors if you have high blood pressure or have had a heart attack or angina. Tadalafil and sildenafil should not be mixed with nitrates, alpha blockers, or hypertension drugs. Cialis and Viagra should also not be taken by people who are pregnant or breastfeeding. Tell your healthcare provider if you have low blood pressure or heart disease.

Storing Cialis® Together

Cialis and Viagra are both safe, effective ED medications. Choosing which is best, or whether an alternative might be better or safer, is a decision that should be made with a healthcare provider familiar with your health history, lifestyle, and other conditions you may have. The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of Feb. 13, 2026. Visit our coupon pages for updated Cialis and Viagra prices near you. brand team leader for Cialis, Lilly ICOS LLC. "Men can take Cialis Friday evening and choose the moment for romance as late as Sunday morning.

Because Cialis works for up to 36 hours, it allows a man and his partner to relax, forget about planning intimacy and let it happen when the moment is right for them." Cialis, approved by the FDA in November 2003 for the treatment of erectile dysfunction, is the only oral ED treatment shown to improve erectile function up to 36 hours in most men.

Adverse effects

These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of Feb. 13, 2026. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. Cialis and Viagra are both PDE5 inhibitors, so they cause similar side effects.

Tadalafil: the science

“The most common side effects have to do with the vasodilation properties associated with PDE5 inhibitors,” Dr. Gingerich says. “People taking these medications may experience flushing, headaches, or indigestion.” Common side effects of both Viagra and Cialis include: Serious side effects of Cialis and Viagra include: Consult your healthcare provider for a complete list of side effects. PDE5 inhibitors aren’t right for everyone. That’s why it’s essential to disclose your full medical history and medications list (prescription and over-the-counter drugs and supplements) to your healthcare provider before 60 mg generic cialis starting Cialis or Viagra. The absorption of Cialis is not reduced by food, including high-fat foods. Cialis is currently available in more than 60 countries, including Australia, Brazil, Mexico, Canada, the United States and countries throughout Europe.

More than two million patients worldwide have been treated with Cialis since its first introduction in February 2003. Cialis is available by prescription only and is not for everyone.

Dietary and Lifestyle factors

Highlights of prescribing information: CIALIS (tadalafil) tablets, for oral use, Food and Drug Administration (2018) Highlights of prescribing information VIAGRA® (sildenafil citrate) tablets, for oral use, Food and Drug Administration (2017) Onset and duration of action of sildenafil for the treatment of erectile dysfunction, British Journal of Clinical Pharmacology (2002) The role of tadalafil in treated hypertensive patients with erectile dysfunction, The Journal of Clinical Hypertension (2022) Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: A systematic review and meta-analysis, International Journal of Urology and Nephrology (2017) Tadalafil in the treatment of erectile dysfunction, Therapeutics and Clinical Risk Management (2008) Cialis – tadalafil tablet, film coated, DailyMed (2009) Viagra – sildenafil tablet, film coated, DailyMed (2017) Medically accurate: SingleCare’s Medical Review Board analyzes all of our content to confirm it’s in line with current medical advice. Evidence-based: Our content is sourced from reputable U.S.-based healthcare professionals and peer-reviewed research. Trustworthy: All of SingleCare’s content goes through a multi-phase review process by our writers, editors, and Medical Board in order to provide clear and credible information. This release was issued by Lilly ICOS LLC Cialis Leads Market in New Treatment Initiations and Switches for April After only six months, Cialis® (tadalafil)1, the latest oral erectile dysfunction (ED) treatment on the market in the U.S., is challenging Viagra® (sildenafil citrate)2for share of the ED market as Cialis leads in new treatment initiations by urologists3 and switches from other products for April. Cialis is marketed by Lilly ICOS LLC, a joint venture between Eli Lilly and Company (NYSE: LLY) and ICOS Corporation (Nasdaq: ICOS).

Therapeutic Categories

Cialis is the only ED treatment shown to improve erectile function up to 36 hours in most men. Cialis can be taken without regard to food. According to market research firm ImpactRx™ (which tracks the habits of a panel of high prescribing physicians and may reflect emerging trends in doctors’ offices today)4, U.S. urologists initiated treatment with Cialis in April at a rate of more than two-to-one over each of the other oral ED treatments. In fact, Cialis represented 56 percent of new treatment initiations by urologists in April, compared to 21 percent for Levitra (vardenafil HCl)5 and 23 percent for Viagra.6 Based on data from IMS, another source of market information, in April, Cialis represented 30 percent of new ED treatment prescriptions written by urologists, compared to 16 percent for Levitra and 54 percent for Viagra.7 In April, nearly two thirds of all men who switched their oral ED treatment switched to Cialis. Men taking nitrates, often used for chest pain, or certain alpha-blockers for prostate problems or high blood pressure, should not take Cialis.

Such combinations could cause a sudden, unsafe drop in blood pressure. Men should discuss their health status with their doctors to ensure Cialis is right for them and that they are healthy enough for sexual activity.

Further information

By contrast, studies show that the effects of Cialis peak about two hours after taking it. Ultimately, the best medication for a patient should be determined only by a healthcare provider familiar with the person’s medical condition, history, and any medications they may already be taking that could interact with Cialis or Viagra, as well as the patient’s response to treatment. “If my patient asked me, ‘Doc, which one should I start with?” I’d say, ‘Let’s try Viagra first. It’s short-acting, so you’ll get a feel for how your body responds. If you like the effect but want more flexibility, we can switch to Cialis later.’” – Anthea Nwandu, MD Both Cialis and Viagra are brand-name drugs that are available in generic form.

When Pills Don't Work

“ED medications are very rarely covered by insurance, regardless of which one is prescribed,” says Blair Gingerich, Pharm.D., an ambulatory care pharmacist in northern Indiana. However, some plans may cover generic ED medications when an underlying health condition causes erectile dysfunction, or when the medication is taken for a different condition, such as BPH or an enlarged prostate. Without insurance, the retail costs for Cialis and Viagra can vary by pharmacy and location. The average retail price of Cialis is $437 for 30, 5 mg tablets, whereas the average Viagra cost is about $1,064 for 10, 100 mg tablets. The good news is that you can save on prescription drugs by using SingleCare coupons or your free SingleCare prescription discount card. The most common side effects with Cialis were headache, upset stomach, delayed backache and muscle ache.

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Following is information from ImpactRx™ on share of new prescriptions written in April by doctors changing their patients' ED treatment from product to another. In an independent clinical study, more men selected Cialis as their preferred treatment of choice after trying different oral ED medications, primarily because of how long the drug worked.8 This may explain why many men with ED who are on oral treatment are switching to Cialis. The percentages of new prescriptions written by all doctors for oral ED treatments in April broke out as follows: Cialis, 19 percent; Levitra, 14 percent; and Viagra, 67 percent.9 "The early success of Cialis in the U.S. is similar to the trend we saw when it first became available in other countries. Cialis has claimed market shares of 19 percent to 39 percent across Europe, and even higher in best price for cialis 5 mg some other markets," said Leonard Blum, vice president of marketing, ICOS Corporation.

Safety With Other Medications

In the first quarter of 2004, Cialis achieved $108 million in global sales. More than two million men around the world have been treated with Cialis since its first introduction globally last year. "For us, the number of Cialis prescriptions written by urologists is one of the most important indicators of future trends. Urologists are the experts in treating ED. We expected that urologists would be the quickest adopters of Cialis, and the data suggest that these specialists, like their peers overseas, are making Cialis their preferred treatment," said Blum. Although rare, men who experience an erection for more than four hours should seek immediate medical attention.

• In Great Britain, Cialis is available via prescription from healthcare providers.
• The UK pharmacy laws regulate the sale of generic Cialis.
• Purchasing from licensed UK pharmacies ensures safety and efficacy.
• The Medicines and Healthcare products Regulatory Agency (MHRA) approves Cialis.
• Generic Cialis must meet strict quality standards in the UK.
• Online pharmacies may stock generic Cialis, but verify legitimacy.
• Buying from unverified sources can pose health risks.
• Generic Cialis helps improve accessibility due to lower costs.
• Doctors can advise on the appropriate Cialis dosage and use.

Men should not drink alcohol in excess with Cialis. Cialis studies were not designed to assess multiple intercourse attempts after a single dose. ED is defined as the consistent inability to attain and maintain an erection sufficient for sexual intercourse. ED affects an estimated 152 million men and their partners worldwide.10 Experts believe that 80 - 90 percent of ED cases are related to a physical or medical condition, like diabetes, cardiovascular diseases, and prostate cancer treatment, while 10 - 20 percent are due to psychological causes.11,12 In many cases, however, both psychological and physiological factors contribute to the condition.13 Lilly ICOS LLC, a joint venture between ICOS Corporation and Eli Lilly and Company, developed tadalafil for the treatment of erectile dysfunction.

• Generic Cialis is the common name for tadalafil, used to treat erectile dysfunction.
• It is produced by multiple pharmaceutical companies worldwide.
• The drug works by increasing blood flow to the penis.
• Generic Cialis costs significantly less than the brand-name version.
• It typically comes in 2.5mg, 5mg, 10mg, and 20mg doses.
• Cialis has a long-lasting effect, up to 36 hours.
• It should be taken at least 30 minutes before sexual activity.
• Possible side effects include headache, flushing, and muscle pain.
• Consult a doctor before using Cialis, especially with other medications.