13 NONCLINICAL TOXICOLOGY

* The brand listed is a trademark of its respective owner and is not a trademark of About Lilly, a leading innovation-driven corporation, is

1. Why am I using CIALIS?

Store at room temperature away from light and moisture. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Long-term use

HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs. Selected from NATIONAL DRUG DATA FILE (NDDF) data included with permission and copyrighted by First Databank, Inc., 2019. developing a growing portfolio of pharmaceutical products by applying the latest research from its own worldwide laboratories and from collaborations with eminent scientific organizations.

Product	Dosage	Quantity + Bonus	Price
Cialis Professional	20mg	120 + 4 Pills	291.68€ 277.79€	Buy
Cialis Generic	5mg	20 Pills	41.99€ 39.99€	Buy
Cialis Generic	60mg	30 + 2 Pills	85.33€ 81.27€	Buy
Cialis Soft Tabs	20mg	60 + 4 Pills	159.37€ 151.78€	Buy
Cialis Black	80mg	180 + 10 Pills	356.64€ 339.66€	Buy
Cialis Black	80mg	270 + 10 Pills	502.88€ 478.93€	Buy
Cialis Generic	60mg	90 + 6 Pills	196.67€ 187.30€	Buy
Cialis Original	20mg	64 + 4 Pills	274.18€ 261.12€	Buy
Cialis Generic	20mg	360 + 10 Pills	427.34€ 406.99€	Buy
Cialis Generic	40mg	270 + 10 Pills	382.19€ 363.99€	Buy
Cialis Black	80mg	30 + 2 Pills	89.11€ 84.87€	Buy
Cialis Original	20mg	22 + 2 Pills	129.20€ 123.05€	Buy
Cialis Generic	2.5mg	180 + 10 Pills	154.86€ 147.49€	Buy
Cialis Generic	10mg	120 + 6 Pills	178.49€ 169.99€	Buy

This press release contains forward-looking statements about the potential of Cialis for the treatment of benign prostatic hyperplasia and reflects Lilly's current beliefs.

Cialis® (tadalafil) Tablets Recommended for Approval for the Treatment of the Signs and Symptoms of Benign Prostatic Hyperplasia in the European Union

Cialis for use as needed should be taken before sexual activity. It may go to work quickly (in as little as 30 minutes in some men) and can work up to 36 hours.*+ The most common side effects with Cialis are headache, indigestion, back pain, muscle aches, flushing and stuffy or runny nose. Back pain and muscle aches usually go away within two days. Not studied for multiple attempts per dose. +In clinical trials, Cialis for use as needed started to work in 30 minutes for some men who took 20 mg of Cialis for use as needed.

Generic version

When taken as needed, Cialis was shown to improve, up to 36 hours after dosing, the ability of men with ED to have a single successful intercourse attempt. Important Safety Information for Cialis® (tadalafil) tablets What Is The Most Important Information I Should Know About Cialis? take medicines called "nitrates" such as isosorbide dinitrate or isosorbide mononitrate which are often prescribed for chest pain as the combination may cause an unsafe drop in blood pressure use recreational drugs called "poppers" like amyl nitrite and butyl nitrite are allergic to Cialis or Adcirca® (tadalafil), or any of its ingredients. Call your healthcare provider or get help right away if you experience any symptoms of an allergic reaction, such as rash, hives, swelling of the lips, tongue or throat, or difficulty breathing or swallowing After taking a single tablet, some of the active ingredient of Cialis remains in your body for more than 2 days. The active ingredient can remain longer if you have problems with your kidneys or liver, or you are taking certain other medications. However, as with any pharmaceutical product under development, there are substantial risks and uncertainties in the process of development, commercialization, and regulatory review.

Condition	Caution Details	Alternative Actions
Nitrate medication use	Contraindicated due to risk of severe hypotension	Consult doctor
Severe cardiovascular disease	Use with caution; potential cardiovascular risk	Medical assessment
Liver or Kidney impairment	Dose adjustment may be necessary	Regular monitoring
Allergies to tadalafil or excipients	Do not use if allergic	Alternative medication

There is no guarantee that the product will receive additional regulatory approvals.

Further information

What Should I Tell My Healthcare Provider Before Taking Cialis? Ask your healthcare provider if your heart is healthy enough for you to have sexual activity. Before taking Cialis, tell your healthcare provider about all your medical problems, particularly if you have or ever had: heart problems such as chest pain (angina), heart failure, irregular heartbeats, or have had a heart attack high or low blood pressure or have high blood pressure that is not controlled liver or kidney problems or require dialysis retinitis pigmentosa, a rare genetic (runs in families) eye disease severe vision loss, including a condition called NAION a deformed penis shape or Peyronie's disease an erection that lasted more than 4 hours blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia Tell your healthcare provider about all the medicines you take especially if you take: medicines called "nitrates" which are often prescribed for chest pain alpha-blockers often prescribed for prostate problems medicines for HIV or some types of oral antifungal medications some types of antibiotics such as clarithromycin, telithromycin, erythromycin (several brand names exist, please contact your healthcare provider to determine if you are taking this medicine) other medicines or treatments for erectile dysfunction (ED) Cialis is also marketed as Adcirca for the treatment of pulmonary arterial hypertension. Do not take sildenafil citrate (Revatio®)* with Cialis. The most common side effects with Cialis are: headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose.

Drug forms and administration

An erection that won't go away: If you get an erection lasting more than 4 hours, seek immediate medical help to avoid long-term injury. In rare instances, men taking prescription ED tablets, including Cialis, reported a sudden decrease or loss of vision or hearing (sometimes with ringing in the ears and dizziness). It's not possible to determine if these events are related directly to the ED tablets or to other factors. If you have a sudden decrease or loss of vision or hearing, stop taking any ED tablet, including Cialis and call a healthcare provider right away. You are encouraged to report negative side effects of prescription drugs to the protect a man or his partner from sexually transmitted diseases, including HIV serve as a male form of birth control For additional information, talk to your doctor and see full Patient Information at and Prescribing Information at or visit for more information. There is also no guarantee that the product will continue to be commercially successful.

Ingredient	Quantity per Tablet	Purpose	Source
Tadalafil	5 mg	Active pharmaceutical ingredient	Synthetic chemical
Microcrystalline Cellulose	50 mg	Filler and binder	Plant-based
Croscarmellose Sodium	10 mg	Disintegrant	Synthetic polymer
Magnesium Stearate	5 mg	Lubricant	Mineral salt
Hydroxypropyl Methylcellulose	15 mg	Coating agent	Plant derivative

For further discussion of these and other risks and uncertainties, see Lilly's filings with

What side effects can this medication cause?

This copyrighted material has been downloaded from a licensed data provider. The above information is intended to supplement, not substitute for, the expertise and judgment of your health care professional. You should consult your health care professional before taking any drug, changing your diet, or commencing or discontinuing any course of treatment. The opinion is now referred for final action to the Cialis was approved for erectile dysfunction (ED) in the EU in 2002. Cialis for once daily use was approved for the treatment of ED in the EU in 2007.

Overdose symptoms

Cialis 5 mg for once daily use was approved by the It is important to note that Cialis is not to be taken with medicines called "nitrates" such as isosorbide dinitrate or isosorbide mononitrate, which are often prescribed for chest pain, or with recreational drugs called "poppers" like amyl or butyl nitrite, as the combination may cause an unsafe drop in blood pressure. It also should not be taken by those who are allergic to Cialis or Adcirca® (tadalafil), or any of its ingredients. Anyone who experiences any symptoms of an allergic reaction, such as rash, hives, swelling of the lips, tongue or throat, or difficulty breathing or swallowing should call their healthcare provider or get help right away. In addition to the U.S., Cialis for once daily use has been approved to treat the signs and symptoms of BPH in About ED and BPH ED is a condition where the penis does not fill with enough blood to harden and expand when a man is sexually excited, or when he cannot keep an erection. Approximately 50 percent of men between 40-70 years old have ED. the Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study.

Drug Label Information

BPH is a condition where the prostate enlarges, which can cause urinary symptoms. ED and BPH are conditions that may occur in the same patient. Several studies have shown that many men with ED also experience the symptoms of BPH. About Cialis Cialis is currently approved for ED in more than 100 countries throughout the world. Cialis for once daily use is approved to treat ED, the signs and symptoms of BPH, and ED and the signs and symptoms of BPH in men who have both conditions (ED+BPH).

Cialis strengths

Cialis 5 mg for once daily use is the recommended dose to treat BPH and ED+BPH. Cialis for once daily use can help men with ED be ready anytime between doses*, so they do not have to plan sexual activity around taking a pill. It can buy cialis with priligy online also treat the signs and symptoms of BPH. Cialis for once daily use is the only medication approved to treat both ED and the signs and symptoms of BPH. Cialis for use as needed is approved to treat erectile dysfunction (ED). Lower urinary tract symptoms and male sexual dysfunction: the multinational survey of the aging male (MSAM-7). Relationship between lower urinary tract symptoms and erectile dysfunction: results from the Critical analysis of

• Cialis daily pill: convenient once-daily routine.
• Eliminates need for timing before intercourse.
• Lowers anxiety associated with on-demand dosing.
• Enhances spontaneity in relationships.
• Can be used as part of combination therapy with other ED treatments.

the relationship between sexual dysfunctions and lower urinary tract symptoms due to benign prostatic hyperplasia.

• Tablet appearance: yellow, marbled, film-coated.
• Imprinted with "C 5" on one side.
• Available in blister packs or bottles.
• Generic tadalafil 5 mg is also available.
• Prices vary by brand and insurance coverage.

Generic name: Tadalafil 5mg Dosage form: tablet, film coated Drug class: Impotence medications Do not split CIALIS tablets; entire dose should be taken.

Common side effects of Cialis

Do not take this medication with any other product that contains tadalafil or other similar medications used to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, vardenafil). If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call 1-800-222-1222. Canada residents can call 1-844-764-7669.

Duration of action

Do not share this medication with others. If you are taking this medication on a regular schedule and you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up. The recommended starting dose of CIALIS for once daily use is 2.5 mg, taken at approximately the same time every day, without regard to timing of sexual activity.

• Cialis 5 mg is usually prescribed after diagnosis by a doctor.
• Do not take more than one dose in 24 hours.
• Regular use can help maintain consistent blood levels.
• The medication can take up to 2 hours to work.
• Alcohol consumption may reduce its effectiveness.
• Patients should inform their doctor of all medications taken.